Progress in research on metformin in inhibiting tumor metastasis
10.3969/j.issn.1000-8179.20141416
- VernacularTitle:二甲双胍抑制肿瘤细胞转移的研究进展
- Author:
Lei QI
;
Huijuan ZHANG
- Publication Type:Journal Article
- Keywords:
metformin;
tumor cells;
inhibit;
metastasis
- From:
Chinese Journal of Clinical Oncology
2014;(23):1544-1547
- CountryChina
- Language:Chinese
-
Abstract:
Metformin has become the first-line drug for the treatment of type 2 diabetes, which is stably efficacious, safe, and cheap. Previous studies have shown that the application of metformin can decrease the rate of tumor incidence, recurrence, and metasta-sis. It can also improve the prognosis of cancer patients and their lifetime after long-term use. Considering its multiple advantages, met-formin has become an emerging choice for the treatment and prevention of cancer. Therefore, the mechanisms through which metfor-min inhibits tumor metastasis in cancer therapy are worth investigating.
