A new selaginellin derivative from Selaginella pulvinata.
- Author:
Yuan CAO
;
Yongping WU
;
Jinao DUAN
- Publication Type:Journal Article
- From:
Acta Pharmaceutica Sinica
2015;50(2):199-202
- CountryChina
- Language:English
-
Abstract:
Abstract: A new selaginellin derivative named as selaginellin S (1) was isolated from the whole plants of Selaginella pulvinata (Hook. et Grev.) Maxim. (Selaginellaceae), together with a known one (selaginellin M, 2). Compounds 1 and 2 were separated and purified by silica gel and Sephadex LH-20 column chromatography. Their structures were determined on the basis of extensive spectroscopic analysis including IR, MS, 1D and 2D NMR experiments, as well as ECD calculations. Compound 1 is a key intermidiant in the biosynthesis pathway of selaginellins. Compound 2 is first reported in this plant.
