Two new sulfated sesquiterpenoids from Petasites tricholobus.
- Author:
Yong ZHANG
;
Yuanyuan GAO
;
Qi JIA
;
Fujiang GUO
;
Bo LI
;
Zhijian XU
;
Yiming LI
;
Weiliang ZHU
;
Kaixian CHEN
- Publication Type:Journal Article
- From: Acta Pharmaceutica Sinica 2014;49(10):1433-7
- CountryChina
- Language:English
- Abstract: Two new sulfated sesquiterpenoids, megastigman-7-ene-3, 5, 6, 9-tetrol-3-O-β-D-6'-sulfonated-glucopyranoside (1) and 3-O-β-D-6'-sulfonated-glucopyranosyl-6-(3-oxo-2-butenylidenyl)-1, 1, 5-trimethylcyclohexan-5-ol (2), along with one known sesquitepenoid compound icariside B1 (3) were isolated from the whole herb of Petasites tricholobus Franch. Their structures were identified by their chemical and spectroscopic characters. All obtained compounds were tested for their cytotoxicity against four cancer cell lines.