Two new sesquiterpenoids from basidiomycete Tyromyces chioneus.
- Author:
Hua GUO
;
Tao FENG
;
Zhenghui LI
;
Jikai LIU
- Publication Type:Journal Article
- From:
Acta Pharmaceutica Sinica
2014;49(11):1578-81
- CountryChina
- Language:English
-
Abstract:
Two new sesquiterpenoids, named as tyromols A and B (1 and 2), were isolated from cultures of basidiomycete Tyromyces chioneus, along with two previously reported 15-hydroxy-6 α, 12-epoxy-7β, 10αH, 11βH-spiroax-4-ene (3) and agripilol C (4). Compounds 1-4 were separated and purified by silica gel, RP-18, Sephadex LH-20 column chromatography. Their structures were elucidated on the basis of extensive spectroscopic analysis including IR, MS, 1D and 2D NMR experiments.