Relationship between lifestyle interventions and glycemic level in adults with impaired glucose tolerance: A systematic review and meta-analysis
10.3760/cma.j.issn.1000-6699.2014.07.009
- VernacularTitle:生活方式干预对成年糖耐量受损患者血糖影响的系统评价及meta分析
- Author:
Qinghai GONG
;
Yanyan YING
;
Hui LI
;
Guozhang XU
- Publication Type:Journal Article
- Keywords:
Lifestyle;
Intervention;
Impaired glucose tolerance;
meta analysis
- From:
Chinese Journal of Endocrinology and Metabolism
2014;30(7):576-581
- CountryChina
- Language:Chinese
-
Abstract:
Objective To determine the efficacy of lifestyle interventions in adults with impaired glucose tolerance (IGT).Methods MEDLINE (Pub Med),EMBASE,Science Citation Index (SCI),and Cochrane Database were retrieved for articles about the relations of lifestyle intervention and IGT.Searches were limited to English language publications.The RCTs outcome evaluated in this study included 2 h plasma glucose level and fasting plasma glucose,meta-analysis was carried oat by Stata 11.0 among articles for the inclusion and exclusion criteria.The difference of effects was expressed as standardized mean deviation(SMD).Results A total of 10 RCTs studies met the inclusion criteria.Lifestyle interventions were associated with a decline in 2 h plasma glucose and fasting plasma glucose level (SMD =-0.67,P＜0.01 ;SMD =-0.33,P＜0.01),but high heterogeneity was identified in this meta-analysis.Conclusion Physical,dietary and both combined interventions can reduce 2-h plasma glucose and fasting plasma glucose levels in adults with impaired glucose tolerance.As high heterogeneity was identified in this meta-analysis,more high quality research is needed.
