The trends in clinical diagnosis and treatment strategies of differentiated thyroid cancer in pediatrics and adolescents
10.3760/cma.j.issn.2095-2848.2014.04.017
- VernacularTitle:儿童及青少年分化型甲状腺癌诊治策略若干进展
- Author:
Renfei WANG
;
Jian TAN
;
Guizhi ZHANG
- Publication Type:Journal Article
- Keywords:
Thyroid neoplasms;
Surgery,operative;
Radiotherapy;
Iodine radioisotopes;
Child;
Adolescent;
Trends
- From:
Chinese Journal of Nuclear Medicine and Molecular Imaging
2014;34(4):331-334
- CountryChina
- Language:Chinese
-
Abstract:
DTC in pediatric and adolescent patients has lower incidence and is generally reported to have better prognosis.However,compared with DTC in adults,it is more aggressive and the recurrence rate is higher.Surgery and adjuvant radioiodine therapy can minimize the risk of recurrence.Total or near total thyroidectomy combined with central compartment lymph node dissection is the preferred surgical procedure for most of these patients.Radioiodine therapy for ablation of thyroidal remnant or residual disease is recommended in order to reduce the risk of tumor recurrence,but there is slight chance of increased risk of a sec ond primary malignancy (SPM).Long-term follow-up is therefore recommended for the pediatrics and adolescents with DTC after treatment.Multi-disciplinary collaborative management is needed to optimize treatment efficacy and to minimize adverse effects.
