Regulative effect of the canonical Wnt pathway on osteogenesis
10.3760/cma.j.issn.1673-4181.2014.04.013
- VernacularTitle:经典Wnt信号通路对细胞成骨分化的调控作用
- Author:
Qihong QIU
;
Min LIANG
- Publication Type:Journal Article
- Keywords:
The canonical Wnt pathway;
Osteogenesis;
Periodontium;
Treatment
- From:
International Journal of Biomedical Engineering
2014;37(4):242-246
- CountryChina
- Language:Chinese
-
Abstract:
The Wnt signaling pathway,including the canonical and the non-canonical,is a conservative pathway which participates in organ development and tissue metabolism.The canonical Wnt pathway plays an important role in osteogenesis,bone formation and mineralization through the osteogenesis associated transcription factors.The canonical Wnt pathway also regulates osteogenic differentiation of the stem cells in the periodontal tissue and the regulative effect is influenced by the microenvironment.Understanding of the canonical Wnt pathway will contribute to the treatment of some related bone diseases.
