Application of membrane sealing materials in repair of the spinal cord injury
10.3760/cma.j.issn.1673-4181.2014.04.011
- VernacularTitle:膜修复材料在脊髓损伤修复中的研究进展
- Author:
Aihua WANG
;
Guanghao ZHANG
;
Xiaolin HUO
- Publication Type:Journal Article
- Keywords:
Membrane sealing;
Polyethylene glycol;
Poloxamer 188;
Chitosan;
Spinal cord injury
- From:
International Journal of Biomedical Engineering
2014;37(4):233-236
- CountryChina
- Language:Chinese
-
Abstract:
The integrity of the neuronal membrane is important for its specific physiological function.Spinal cord injury (SCI) can result in immediate disruption of neuronal membranes.Now,a novel treatment method for SCI is sealing the compromised membranes at the early stage of SCI.In this article,recent development of membrane repair agents in treating SCI is discussed,including polyethylene glycol(PEG),poloxamer 188(P188),chitosan and some nanomaterials.At the same time,problems remained in recent researches are reviewed and the prospect is discussed.