Study of relationship between levels of hs-CRP and IL-6 with restenosis after stent angioplasty in cerebral arterial stenosis
10.3969/j.issn.1671-8348.2014.27.006
- VernacularTitle:hs-CRP和IL-6动态变化与脑动脉狭窄支架成形术后再狭窄的相关性研究
- Author:
Changming WEN
;
Xinkai WANG
;
Baochao ZHANG
- Publication Type:Journal Article
- Keywords:
interleukin-6;
high sensitive C-reactive protein;
cerebral artery stenosis;
stent angioplasty;
restenosis
- From:
Chongqing Medicine
2014;(27):3567-3569
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the relationship between the dynamic changes of hs-CRP and IL-6 with restenosis after stent angioplasty in cerebral arterial stenosis .Methods 65 patients with cerebral artery stenosis stent angioplasty in Nanyang Mu-nicipal Central Hospital from March 2011 to March 2013 were retrospectively analyzed .The changes of hs-CRP and IL-6 levels be-fore operation and at different postoperative time points were observed and their correlation with vascular restenosis was anlyzed . Results (1)The cerebral artery stenosis degree and serum hs-CRP and IL-6 levels were positively correlated(P<0 .05) .(2)Com-paring the hs-CRP and IL-6 levels at different time points showed that the postoperative hs-CRP and IL-6 levels were significantly increased ,reached the highest at postoperative 12 h and then gradually declined .The hs-CRP and IL-6 levels on postoperative 7 d in the patients with restenosis were significantly higher than those in the patients without restenosis (P<0 .05) .(3)The hs-CRP and IL-6 levels at postoperative 6 months in the patients without restenosis were significantly decreased compared with before opera-tion ,but which in the patients with restenosis had no statistically significant differences (P>0 .05);△hs-CRP and △IL-6 had sta-tistically significant differences between the patients with restenosis and the patients without restenosis (P<0 .05) .Conclusion hs-CRP and IL-6 may play an important role in the process of restenosis after stent angioplasty in cerebral arterial stenosis .Monitoring the dynamic changes of hs-CRP and IL-6 has certain value for evaluating vascular restenosis .
