Risk factors and drug resistance of elderly patients with ventilator associated pneumonia
10.3760/cma.j.issn.1008-6706.2014.20.012
- VernacularTitle:老年人呼吸机相关肺炎的危险因素及耐药性分析
- Author:
Jianling LI
- Publication Type:Journal Article
- Keywords:
Pneumonia,ventilator-associated;
Risk factors;
Drug resistance;
Aged
- From:
Chinese Journal of Primary Medicine and Pharmacy
2014;(20):3074-3075
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the risk factors and drug resistance in elderly patients with ventilator associated pneumonia(VAP).Methods From April 2012 to April 2014,the clinical data of 160 senile VAP patients in ICU were selected,the relationship of VAP with age,duration of mechanical ventilation,whether tracheotomy and the original diseases were analyzed .The drug susceptibility test was made to analyze the drug resistance .Results The incidence rates of VAP in patients with chronic obstructive pulmonary disease ,duration of mechanical ventilation more than 7d,over 65 years old (16.8%,13.4%,18.5%) were significantly increased (χ2 =11.592,11.989,13.187,all P<0.05),the incidence rate of VAP did not increase in the tracheotomy (P>0.05).The main pathogenic bacteria in elderly patients with VAP infection were Pseudomonas aeruginosa , Klebsiella pneumoniae , Escherichia coli , Enter-obacter cloacae .Drug sensitive experiment found that patients had multi-drug resistance ,the strains had higher resist-ance rate to ampicillin,piperacillin,ciprofloxacin,ofloxacin and ceftriaxone .Conclusion The original chronic lung disease,mechanical ventilation time and over 65 years old are risk factors of elderly VAP ,the patients have multi-drug resistance ,and the strains show the highest resistance to ampicillin .
