Progress in Research on Immunological Effect of Macrophages in Ulcerative Colitis
10.3969/j.issn.1008-7125.2014.08.013
- VernacularTitle:巨噬细胞免疫效应与溃疡性结肠炎的研究进展
- Author:
Dan ZHANG
;
Xuegui HUA
;
Jie LIU
;
Xiaoming FENG
;
Chen QIAN
;
Kai WEI
;
Zhijun WENG
;
Huangan WU
;
Xiaopeng MA
- Publication Type:Journal Article
- Keywords:
Macrophages;
Immunomodulation;
Cellular Microenvironment;
Colitis,Ulcerative;
Moxibustion
- From:
Chinese Journal of Gastroenterology
2014;(8):500-503
- CountryChina
- Language:Chinese
-
Abstract:
Macrophages( Mφ)play an important role in the regulation of immune reaction. Different kinds of cellular microenvironment influence the phenotypes and function of Mφ and induce different immunological effect. Researches showed that there was a strong correlation between the dysfunction of Mφ and development of ulcerative colitis( UC ). Targeted regulation on immunological activity of Mφ may improve the clinical manifestations and pathological changes in UC. Regulation of the activity and migration of Mφ through changing microenvironment might be one of the potential mechanisms of moxibustion in treating UC. Progress in research on immunological effect of Mφ in UC was summarized in this review article.
