LncRNAs in Digestive System Diseases
10.3969/j.issn.1008-7125.2014.07.007
- VernacularTitle:LncRNAs在消化系统疾病中的研究进展
- Author:
Jun ZHOU
;
Shangao LI
- Publication Type:Journal Article
- Keywords:
LongNoncodingRNAs;
DigestiveSystemDiseases;
Diagnosis;
Therapy;
Prognosis
- From:
Chinese Journal of Gastroenterology
2014;(7):428-431
- CountryChina
- Language:Chinese
-
Abstract:
Long noncoding RNAs( lncRNAs)are a class of non-protein-coding RNA species that are greater than 200 nucleotides in length. LncRNAs regulate gene expression at the epigenetic,transcriptional and post-transcriptional levels, and are widely implicated in the physiological and pathological processes. Recent evidences indicated that lncRNAs play important roles in the development and progression of many digestive system diseases. Studies focusing on lncRNAs may provide valuable data for the prediction,diagnosis,therapeutics and prognosis assessment for these diseases. In this article,the fundamental principles and progress in study on lncRNAs in digestive system diseases were summarized.
