Research advances of MicroRNAs in early embryonic development
- VernacularTitle:MicroRNAs 在早期胚胎发育中的研究进展
- Author:
Shenglin JIANG
;
Xiufeng LING
;
Junqiang ZHANG
- Publication Type:Journal Article
- Keywords:
MicroRNAs;
Mechanism;
Early embryonic development
- From:
Journal of Medical Postgraduates
2014;(9):986-989
- CountryChina
- Language:Chinese
-
Abstract:
MicroRNAs(miRNAs) is a class of small endogenous noncoding RNAs with 22 nucleotides.They can negatively regulate gene expression by inhibiting target mRNAs′translation or degrading mRNAs .Up to now, it has been proved that miRNAs play an important role in cellular proliferation , apoptosis , cell differentiation , and embryonic development .In this article , mechanism and function of miRNAs , principal methodologies in the research of miRNAs and the latest development of miRNAs in early embryonic de -velopment are discussed .
