Advance of the relationship of iron deficiency and pulmonary arterial hypertension
- VernacularTitle:铁缺乏与肺动脉高压的研究进展
- Author:
Jie ZHANG
;
Jun XU
- Publication Type:Journal Article
- Keywords:
Pulmonary arterial hypertension;
Iron deficiency;
Hepcidin
- From:
Journal of Medical Postgraduates
2014;(9):1002-1005
- CountryChina
- Language:Chinese
-
Abstract:
Pulmonary hypertension has now become a common diseases threaten to human health .There are many factors that can cause pulmonary hypertension , such as heredity, immune injury, inflammation and endothelial function damage , etc.In recent years, studies have found that patients with pulmonary hypertension commonly have the phenomenon of iron deficiency , and intravenous iron agent can improve that , but the specific mechanism is unclear .Iron in the human body mainly is controlled by a protein called hepcidin, it inhibits iron flow from the gastrointestinal to the blood .Thus, intravenous iron administration can provide new options for the treatment of pulmonary hypertension .This paper reviews the progress of the iron deficiency and pulmonary hypertension .
