Effect of Glutamine in stress ulcer Prevention and treatment of acute cerebral infarction Patients
l0.3760/cma.j.issn.l008-63l5.20l4.l3.005
- VernacularTitle:谷氨酰胺防治急性脑梗死患者应激性溃疡效果观察
- Author:
Xuemin ZHANG
;
Juan XIE
;
Wei LU
;
Gang LU
- Publication Type:Journal Article
- Keywords:
Glutamine;
Acute cerebral infarction;
Stress ulcer
- From:
Clinical Medicine of China
2014;(z1):12-13
- CountryChina
- Language:Chinese
-
Abstract:
Objective To Apply appropriate dose of Glutamine(Gln)(300mG/d)for patients with acute cerebral infarction,and observe its preventinG and curinG function to the stress ulcer. Methods Sixty cases patients of acute cerebral infarction were observed and divided into the conventional treatment Group( 30 cases),Glutamine treatment Group( GLU,30 cases). Gastric pH value of patients was tested before treatment and after one week treatment. The stool or vomit occult blood positive( OB+)number of patients within one week, OB( +) duration and the number of patients need blood filterinG were observed. Results There was no siGnificant difference between the conventional treatment Group and the GLU Group in the Gastric juice PH value before treatment(t=0. 647,P>0. 05). After one week treatment,the Gastric juice PH value of the GLU Group was siGnificant hiGher than the conventional treatment Group(t=5. 25,P<0. 05);the number of OB( +)of GLU Group were less than the conventional treatment Group,but there was no statistical siGnificant difference(χ2=0. 577,P>0. 05);the OB( +)duration of GLU Group was less than the conventional treatemnt Group,and there was satistical siGnificant difference(t =4. 768,P <0. 05);the number of blood filterinG of GLU to treat stress ulcer was less than conventional treatment Group,and there was satistical siGnificant difference(χ2=l. 0l6,P>0. 05). Conclusion SupplementinG appropriate dose of Glutamine in patients with acute cerebral infarction can reduce the incidence of stress ulcer,decrease medical expenses.
