Association between ankle-brachial index and serum uric acid level in patients at high risk of cardiovascular diseases
10.3969/j.issn.1009-0126.2014.08.003
- VernacularTitle:心血管高危患者踝臂指数与血尿酸水平的相关性分析
- Author:
Jie GUAN
;
Ying GAO
;
Zhilian LIU
- Publication Type:Journal Article
- Keywords:
hypertension;
diabetes mellitus;
uric acid;
cardiovascular diseases;
ankle-brachial index
- From:
Chinese Journal of Geriatric Heart Brain and Vessel Diseases
2014;(8):792-794
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the association between ankle-brachial index (ABI) and serum uric acid (SUA) level in patients at high risk of cardiovascular diseases .Methods Three hundred and sixty-three patients with hypertension and diabetes mellitus (DM ) were divided into hyper-tension group (n=189) ,hypertension plus DM group (n=123) ,and DM group (n= 51) .Their ABI was assayed ,SUA level was measured ,and other risk factors for cardiovascular diseases were detected such as BMI ,systolic and diastolic pressure ,serum levels of TG ,TC ,HDL-C ,LDL-C and HbA1c .Association of SUA level and ABI with other clinical indexes was analyzed by partial cor-relation analysis .Results The systolic and diastolic pressure ,serum levels of TG ,HDL-C and HbA1c were significantly different in 3 groups (P<0 .05) .The ABI was significantly higher in hypertension group and DM group than in hypertension plus DM group ,and negatively related with SUA level after adjustment for hypertension and DM history ,age ,gender ,BMI ,serum levels of TG ,TC ,HDL-C ,LDL-C and HbA1c ,systolic and diastolic pressure (r= -0 .235 ,P=0 .012) . Conclusion ABI is associated with SUA level in patients at high risk of cardiovascular diseases .
