Artery stiffness is an independent factor for left ventricular remodeling and cardiac function in coronary heart disease patients
10.3969/j.issn.1009-0126.2014.08.009
- VernacularTitle:冠心病患者动脉僵硬度与左心室重构及心功能的相关性
- Author:
Wen MAO
;
Miaomiao ZHANG
;
Di WU
- Publication Type:Journal Article
- Keywords:
coronary disease;
arteriosclerosis;
ventricular remodeling;
coronary angiography;
blood flow velocity
- From:
Chinese Journal of Geriatric Heart Brain and Vessel Diseases
2014;(8):811-814
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the correlation of artery stiffness with left ventricular remodeling and cardiac function in coronary heart disease (CHD) patients .Methods Four hundred and eighty patients were divided into CHD group (n=373) and non-CHD group(n=107)according to their coronary angiography .Patients in CHD group were further divided into normal left ventricular re-modeling group (n=139) and abnormal left ventricular remodeling group (n=243) .Their brachi-al-ankle pulse wave velocity (BaPWV ) was measured .The patients underwent echocardiography and 42 patients in CHD group received Doppler tissue imaging .Results The BaPWV was signifi-cantly higher in CHD group than in non-CHD group (P<0 .01) and in abnormal left ventricular remodeling group than in normal left ventricular remodeling group (1689 ± 305 cm/s vs 1508 ± 280 cm/s ,P< 0 .05) .The BaPWV was positively related with the IVST ,PWT ,RWT ,LVMI ,E/Ea and negatively related with the LVEF ,Ea ,Ea/Aa in CHD group (P<0 .05 ,P<0 .01) .Partial cor-relation analysis showed that the BaPWV was significantly related with the IVST ,PWT ,RWT , LVMI ,LVEF ,Ea ,Ea/Aa and E/Ea when the effect of hypertension ,etc ,was excluded (P<0.01) .Multivariate regression analysis demonstrated that the BaPWV was an independent factor for LVMI and LVEF .Conclusion BaPWV is an independent factor for left ventricular remodeling and cardiac function in CHD patients .
