Role of Beta-blockers in Treatment of Heart Failure.
10.5124/jkma.2007.50.3.274
- Author:
Duk Kyung KIM
1
;
Sue Jin KIM
Author Information
1. Department of Internal Medicine, Sungkyunkwan University School of Medicine, Korea. dkkim@smc.samsung.co.kr, koroh78@empal.com
- Publication Type:Original Article
- Keywords:
Heart failure;
Beta-blocker
- MeSH:
Heart Failure*;
Heart*;
Hospitalization;
Humans;
Norepinephrine
- From:Journal of the Korean Medical Association
2007;50(3):274-278
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Anti-adrenergic medication is very important to the treatment of chronic heart failure because a failing human heart is adrenergically activated. The increase in cardiac adrenergic drive and circulating norepinephrine are damaging to a failing heart. Certain beta-blockers have been shown to improve the cardiac function and symptoms and to reduce the risk of death and hospitalization in patients with heart failure. Recently, the third-generation beta-blockers have emerged for the treatment of heart failure. This article reviews the neurohormonal pathophysiology of heart failure and the different beta-blockers and their effects.
