Antimicrobial resistance in 42 cases of neonate septicemia caused by Streptococcus agalactiae infection
10.3969/j.issn.1673-4130.2014.17.017
- VernacularTitle:42例新生儿无乳链球菌败血症耐药性分析
- Author:
Weihong FAN
;
Mancang ZHAO
;
Jie LIU
- Publication Type:Journal Article
- Keywords:
Streptococcus agalactiae;
drug resistance;
antibiotic;
septicemia;
neonate
- From:
International Journal of Laboratory Medicine
2014;(17):2309-2310
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate clinical features and drug resistance of neonate septicemia caused by Streptococcus agalac-tiae in the hospital and to provide clinical guidance for treatment.Methods 42 Streptococcus agalactiae isolates in the hospital were identified and their department distribution as well as drug susceptibility was determined by using automatic VITEK-2 system and criteria released by CLSI in 2012.Results The number of cases in preterm neonatal intensive care unit,full-term neonatal intensive care unit,pediatric intensive care unit and extremely preterm neonatal intensive care unit were 3,26,7 and 6,respectively.The drug resistance rates of the isolated Streptococcus agalactiae to ampicillin,erythromycin,clindamycin,quinupristin/dalfopristin,linezolid, penicillin,tetracycline,tigecycline,vancomycin and levofloxacin were 0.0%,69.0%,71.4%,0.0%,0.0%,0.0%,74.4%,0.0%, 0.0% and 38.1%,respectively.Conclusion The antimicrobial resistance rates of Streptococcus agalactiae which caused neonatal septicemia in our hospital are relatively high.Ampicillin and penicillin are recomended in treatment for neonate septicemia caused by Streptococcus agalactiae .
