Effects of anatomical and nonanatomical hepatectomy on the prognosis of patients with HCC
10.3969/j.issn.1005-6483.2014.09.018
- VernacularTitle:解剖性和非解剖性肝切除对肝细胞癌患者预后的影响
- Author:
Yumin LI
- Publication Type:Journal Article
- Keywords:
anatomical hepatectomy;
nonanatomical hepatectomy;
HCC;
prognosis
- From:
Journal of Clinical Surgery
2014;(9):669-672
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the effects of anatomical and nonanatomical hepatectomy on the prognosis of patients with hepatocellular carcinoma(HCC).Methods A total of 62 HCC patients were enrolled,including 33 cases of anatomical hepatectomy(Group AH)and 29 cases of nonanatomical hepa-tectomy(Group IH).The operation situation and hematocrystallin(HB)loss were record.Fasting venous blood of HCC patients were extracted for detection of circulating AFP mRNA expression.The recurrence, mortality and complication rate were recorded at the same time.Results The operative time of Group AH was significantly higher than that of Group IH,while the bleeding volume and HB loss were lower(P<0.05).There were no significant differences in AFP mRNA expression and recurrence rate.The short-term mortality rate of Group AH was lower than Group IH(P<0.05 ),but their long-term mortality rates were similar(P>0.05 ).There was no significant difference in complication rate between groups.Patients of Group AH got more hepatosis due to liver cirrhosis or fibrosis,while patients of Group IH got more bleeding or infection due to the central tumor.Conclusion Anatomical hepatectomy has advantages in protecting artery and improving prognosis for HCC patients,but it has surgical risks for patients with serious patholog-ical damage in hepatic lobes,and nonanatomical hepatectomy may be considered.
