The evaluation of traditional laboratory examination in identifying the rise of peripheral blood leukocytes
10.3969/j.issn.1673-4130.2014.17.015
- VernacularTitle:传统实验室检查项目在鉴别外周血白细胞升高中的应用评价
- Author:
Yanhong ZHANG
;
Hui WANG
;
Xuan HU
;
Changyou YUAN
- Publication Type:Journal Article
- Keywords:
infection;
glucocorticoid;
C reactive protein;
count of neutrophilic granulocyte;
neutrophilicalkaline phos-phatase score
- From:
International Journal of Laboratory Medicine
2014;(17):2305-2306
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the role of several traditional laboratory examinations in identifying the cause of WBC count increase,which might be the adverse reaction of glucocorticoid or infection.Methods 74 patients treated in the hospital from Jan. 2011 to Dec.2012 were recruited in the study.Glucocorticoid without Infection(n =15 ),Infection without Glucocorticoid(n =29) and Infection with Glucocorticoid(n=30)Group were devided according to the type of disease and therapies.After being treated for 0,3,7 d,respectively venous blood samples of patients were collected to determine the concentration of CRP,WBC count,leukocyte classification and NAP score.CRP was used as the Judgment index for the degree of infection,the changes of other indexes were compared.Results Compared with the Infection without Glucocorticoid Group,the CRP concentration of the Infection with Glu-cocorcoid Group was becoming lower(P >0.05).The Non-infection with Glucocorticoid Group applied glucocorticoid for 3 days and 7 days respectively,the count of neutrophilic granulocyte and NAP score increased significantly compared with that before glucocor-ticoid application(P <0.01)while the count of lymphocyte reduced(P <0.05)and no significant change in the count of eosnophils (P >0.05).Conclusion The increase of WBC after glucocorticoid can not be identified whether it is the adverse reaction of glu-cocorticoid or aggravated infection by using classification of leukocyte,the increasing amount of WBC and NAP score.
