Treatment of malignant paravertebral and mesenchymal tumor pain with cryoablation
10.3969/j.issn.1000-8179.20140204
- VernacularTitle:冷冻消融治疗椎旁恶性间叶组织肿瘤疼痛疗效研究
- Author:
Yong LI
;
Zhi GUO
;
Wenge XING
;
Haitao WANG
;
Xueling YANG
;
Changfu LIU
- Publication Type:Journal Article
- Keywords:
cryoablation;
paravertebral;
mesenchymal tumor;
pain
- From:
Chinese Journal of Clinical Oncology
2014;(16):1052-1056
- CountryChina
- Language:Chinese
-
Abstract:
Objective:This study aimed to analyze the feasibility, safety, and efficacy of cryoablation in treating pain caused by malignant paravertebral and mesenchymal tumor. Methods:Cryoablation was performed in 31 patients with unresectable and painful malignant paravertebral and mesenchymal tumors whose pain was poorly controlled by conventional treatment methods. Tumors ranged in size from 3 cm to 20 cm. Pain experienced by the patient was assessed using the Brief Pain Inventory (BPI) at 0, 1 day, 1 week, 1 month, and 3 months post-cryoablation. Results:BPI scores were divided into two categories, i.e., the influence and the se-verity of pain. Both categories showed downward trend after cryoablation. Pain severity score significantly decreased (P=0.001, t=3.862;P=0.031, t=2.261) 1 day and 1 month after cryoablation. Pain influence score also significantly decreased (P=0.016, t=2.566;P=0.036, t=2.195) 1 day and 1 week after cryoablation. Two patients (6.45%) had mild complications, and no serious complication was ob-served. Conclusion:Cryoablation is a low-risk and well-tolerated topical treatment for pain caused by unresectable malignant paraverte-bral and mesenchymal tumors.
