In vitro activities of Minocycline and polymycin B against pan-drug resistant Acinetobacter baumanii
10.3969/j.issn.1673-4130.2014.17.032
- VernacularTitle:多黏菌素B和米诺环素对泛耐药鲍曼不动杆菌体外抗菌活性的比较
- Author:
Ling ZHANG
;
Yun CHEN
;
Houzhao WANG
;
Lingyun WEI
;
Ming GUO
- Publication Type:Journal Article
- Keywords:
pan-drug resistant;
Acinetobacter baumanii;
Minocycline;
polymycin B
- From:
International Journal of Laboratory Medicine
2014;(17):2341-2342
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the in vitro susceptibility of Minocycline and polymycin B against clinical islates of pan-drug resistant Acinetobacter baumanii ,to provide laboratory support for clinical treatment for drug selection.Methods The susceptible test of Minocycline and polymycin against 39 isolates of pan-drug resistant Acinetobacter baumanii were determined by K-B meth-od.Results 38 strains of pan-resistant Acinetobacter baumanii were sensitive to polymyxin B,sensitive rate was 97.4%,20 strains sensitive to minocycline,the sensitivity rate was 51.3%.polymyxin B sensitivity was more sensitive than Minocycline (P < 0.05). Conclusion Polymycin B had strong activit ies against pan-drug resistant Acinetobacter baumanii .