Determination of 15 Phthalate Esters in Drinking Water by Solid Phase Extraction-Ultra Performance Liquid Chromatography-Tandem Mass Spectrometry
10.11895/j.issn.0253-3820.140172
- VernacularTitle:固相萃取-超高效液相色谱串联质谱法测定饮用水中15种邻苯二甲酸酯
- Author:
Haijing ZHANG
;
Xiaojian HU
;
Shaobin LIN
- Publication Type:Journal Article
- Keywords:
Drinking water;
Phthalate esters;
Solid phase extraction;
Ultra performance liquid chromatography-tandem mass spectrometry
- From:
Chinese Journal of Analytical Chemistry
2014;(9):1281-1287
- CountryChina
- Language:Chinese
-
Abstract:
A method of solid phase extraction coupled with ultra performance liquid chromatography-tandem mass spectrometry ( SPE-UPLC/MS/MS) was developed for the determination of 15 phthalate esters. Drinking water samples were concentrated by C18 SPE cartridge. The fifteen phthalate esters were separated on a phenyl column with gradient elution using methanol and water as mobile phases. Multiple reaction monitoring ( MRM) acquisition under positive ion mode was performed. The external matrix standard solutions were used for the quantitative determination. The linear range of Di-n-butyl phthalate was 0. 63-1000 μg/L. The other 14 phthalate esters showed good linearity in the range of 0 . 002-500 μg/L with the correlation coefficients more than 0. 9970. The limits of quantification ( LOQ) were 2. 2-632 ng/L. The spiked recoveries ranged from 81 . 3% to 109%. The relative standard deviations were less than 14%.
