Recent progress of Notch-1 signaling pathway in tumor research
- VernacularTitle:Notch-1信号通路在肿瘤中的研究进展
- Author:
Qingqing ZHANG
;
Wei CHEN
;
Senlin ZHANG
- Publication Type:Journal Article
- Keywords:
Notch-1;
Tumor;
Signaling transduction
- From:
Journal of Medical Postgraduates
2014;(8):871-873
- CountryChina
- Language:Chinese
-
Abstract:
As one of members of the Notch gene family , Notch-1 signaling pathway plays an important role in the processing of cell proliferation , differentiation , survival and apoptosis .The abnormal expression of Notch-1 is closely related to tumorigenesis and de-velopment .In recent years , many studies have focused on the relationship between the Notch-1 signaling pathway and tumor .This arti-cle reviews the achievement of Notch-1 signaling pathway in recent tumor researches .
