Research progress on fibroblast growth factor receptor 1 in breast carcinoma
- VernacularTitle:成纤维生长因子受体1在乳腺癌中的研究进展
- Author:
Lixia ZHANG
;
Qingxia LI
- Publication Type:Journal Article
- Keywords:
Basic fibroblast growth factor;
Fibroblast growth factor receptor 1;
Signaling pathway;
Breast cancer
- From:
Journal of Medical Postgraduates
2014;(8):884-887
- CountryChina
- Language:Chinese
-
Abstract:
Fibroblast growth factor receptor ( FGFR) is one of the molecules involved in tumor formation , and plays an impor-tant role in cell proliferation , angiogenesis and migration .In this article, we review the role of FGFR signal pathway in breast cancer , the correlation with the risk and prognosis , the function of FGFRs as potential therapeutic targets for breast cancer and discuss various treatment strategies of targeted FGFR 1 in clinical trials .
