Diagnostic Difficulties in Fine Needle Aspiration of Benign Salivary Glandular Lesions.
- Author:
Hye Jung JO
1
;
Hyo Jung AHN
;
Soojin JUNG
;
Hye Kyoung YOON
Author Information
1. Department of Pathology, Busan Paik Hospital, Inje University College of Medicine, Busan, Korea. pathyoon@inje.ac.kr
- Publication Type:Original Article
- Keywords:
Biopsy, fine-needle;
Benign lesion;
Salivary glands
- MeSH:
Adenoma, Pleomorphic;
Biopsy, Fine-Needle;
Salivary Glands
- From:Korean Journal of Pathology
2012;46(6):569-575
- CountryRepublic of Korea
- Language:English
-
Abstract:
BACKGROUND: The diagnostic accuracy of fine needle aspiration cytology (FNAC) of salivary lesions is relatively high, but cytologic interpretation might be confusing if the sample is lacking typical cytologic features. METHODS: There were 77 cases of benign salivary lesions, consisting of pleomorphic adenoma (PA) in 61 cases, Warthin's tumor (WT) in 12 cases, and other benign lesions in 4 cases. The causes of the discrepancies between the FNAC and the histologic diagnoses were evaluated. RESULTS: Major discrepancies were noted in 4 of the 61 PA cases, and in 1 of 12 WT cases. The causes of the major discrepancies were a mislabeled site in 1 PA and 1 WT case, and an interpretation error in 3 PA cases. Minor discrepancies were more common in the WT cases (7 of 12 cases) than in the PA cases (11 of 61 cases). The causes of the minor discrepancies were a mislabeled site in 1 PA and 1 WT case, an inadequate sample in 7 PA and 2 WT cases, a lack of typical cytomorphology in 2 PA and 2 WT cases, and an interpretation error in 1 PA and 2 WT cases. CONCLUSIONS: To increase the diagnostic accuracy in the benign salivary lesions, recognition of both characteristic and less typical cytomorphology is needed.
