Therapeutic effect of thrombus suction in patients with acute ST-segment elevation myocardial infarc-tion
10.3969/j.issn.1008-0074.2014.04.17
- VernacularTitle:血栓抽吸对急性 ST 段抬高心肌梗死患者的疗效
- Author:
Yang ZHUO
;
Zhaofang YIN
;
Liang ZHANG
;
Yuqi FAN
;
Li FAN
;
Zuojuan XU
;
Changqian WANG
- Publication Type:Journal Article
- Keywords:
Myocardial infarction;
Thrombosis;
Angioplasty,transluminal,percutaneous coronary
- From:
Chinese Journal of cardiovascular Rehabilitation Medicine
2014;23(4):420-424
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To explore therapeutic effect and prognosis of thrombus suction in patients with acute ST seg-ment elevation myocardial infarction (STEMI)during percutaneous coronary intervention (PCI).Methods:A total of 105 STEMI patients were enrolled and divided into thrombus suction + PCI group (n=34,received thrombus suction + PCI therapy)and routine PCI group (n=71,received routine PCI treatment).Postoperative TIMI flow, cardiac function during hospitalization,incidence of major adverse cardiovascular events (MACE)and rehospitaliza-tion within one-year follow-up after PCI were compared between two groups.Results:Compared with routine PCI group,there were significant reductions in peak values of creatine kinase isoenzyme [CK-MB,(236.62± 133.00) ng/ml vs.(186.47±69.20)ng/ml]and creatine kinase [CK,(2833.39± 198.70)ng/ml vs.(2129.59± 199.40) ng/ml],peak time of CK-MB [(12.38±6.70)h vs.(9.65±3.90)h]and CK [(12.80±8.10)h vs.(9.68± 3.50)h]after blood flow recovery,P < 0.05 all in thrombus suction + PCI group;there were downtrend of MACE (19.7% vs.8.8%)and rehospitalization rate (66.2% vs.50.0%)in thrombus suction + PCI group,but no significant difference between routine PCI group and thrombus suction + PCI group during one-year follow-up,P >0.05. Conclusion:Thrombus suction is help for improving patients condition,reducing enzymology level may be effect improving prognosis.
