Risk factors of healthcare-associated infection in patients with craniocere-bral operation
10.3969/j.issn.1671-9638.2014.08.004
- VernacularTitle:神经外科颅脑手术患者医院感染危险因素分析
- Author:
Honghui RONG
;
Yunxi LIU
;
Shengshan CAO
;
Xiuying WANG
;
Mingmei DU
;
Jijiang SUO
;
Yubin XING
- Publication Type:Journal Article
- Keywords:
neurosurgery department;
craniocerebral operation;
healthcare-associated infection;
risk factor
- From:
Chinese Journal of Infection Control
2014;(8):463-466
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate risk factors for healthcare-associated infection(HAI)in patients with craniocerebral operation,and provide reference for the prevention and control of HAI.Methods A total of 4 246 cases of craniocerebral surgery in a neurosurgery department from January 2010 to December 2012 were enrolled in the study,the risk fac-tors for HAI were analyzed.Results Of 4 246 cases of craniocerebral surgery,393 patients developed 446 times of post-operative HAI,HAI incidence rate was 9.26%,case infection rate was 10.50%,which were higher than inci-dence (2.02%)and case infection rate (3.02%)of HAI of all hospital during the same period,the difference was statistically significant (χ2 =811 .06,629.30,respectively,P <0.001).The major infection site was central nervous system (56.50%),followed by respiratory system (27.36%).Unconditional univariate logistic regression analysis showed that sex,age,community-acquired infection,primary disease,operative time,length of stay in intensive care unit (ICU)before infection,the number of surgery,invasive procedures and nasogastric tube,the difference was statistically significant (all P <0.05 ).Multivariate logistic regression analysis showed that sex,elderly pa-tients,congenital brain diseases,stay in ICU>7 d,antimicrobial use >7 d,central venous and urinary tract cathe-terization,invasive ventilator were risk factors for HAI in patients with craniocerebral operation.Conclusion The incidence of HAI in patients with craniocerebral operation is high,effective preventive and control measures accord-ing to risk factors should be strengthened to reduce the incidence of HAI.
