Influence factors of vincristine' s adverse reaction
10.3760/cma.j.issn.1673-422X.2014.08.005
- VernacularTitle:长春新碱不良反应影响因素的研究进展
- Author:
Cheng HUANG
;
Xiaoli MA
- Publication Type:Journal Article
- Keywords:
Vincristine;
Medication systems;
Adverse reaction;
Influence factors
- From:
Journal of International Oncology
2014;(8):574-576
- CountryChina
- Language:Chinese
-
Abstract:
During the treatment of pediatric tumor,vincristine is one of the most widely used and most effective drugs. However,the adverse reactions have limited its clinical application. In recent years,studies have found that the metabolism of vincristine are different in different races and different individuals,and co-ad-ministration with certain drugs such as imidazoles antifungal drugs may enhance its adverse reaction. Resear-ches on new drug delivery system provide a new idea for reducing the adverse reactions of vincristine and impro-ving its bioavailability.
