Progression of tumor dormancy models
10.3760/cma.j.issn.1673-422X.2014.08.002
- VernacularTitle:肿瘤休眠模型研究进展
- Author:
Menghan ZHU
;
Weiwei FENG
- Publication Type:Journal Article
- Keywords:
Neoplasms,experimental;
Models,animal;
Dormancy period
- From:
Journal of International Oncology
2014;(8):564-567
- CountryChina
- Language:Chinese
-
Abstract:
Tumor dormancy is a state that tumor cells long-term exist in human body,without obvious growth. Dormant cell is one of the origins of tumor recurrence or metastasis. The exact mechanism of tumor dor-mancy is still unclear. Combined with cellular and molecular biological techniques,tumor cell transplantation and culture in vitro can establish experimental tumor dormancy-recurrence models. These in vivo and in vitro models can be used to investigate mechanisms of tumor dormancy and to explore novel treatments.
