An Outbreak of Trichinosis with Molecular Identification of Trichinella sp. in Vietnam.
- Author:
Nguyen Van DE
1
;
Nguyen Vu TRUNG
;
Nguyen Hong HA
;
Vu Thi NGA
;
Nguyen Minh HA
;
Pham Thanh THUY
;
Le Van DUYET
;
Jong Yil CHAI
Author Information
1. Department of Parasitology, Hanoi Medical University, Vietnam. ngvdeyhn@gmail.com
- Publication Type:Case Reports ; Research Support, Non-U.S. Gov't
- Keywords:
Trichinella spiralis;
muscle pain;
pork;
fever;
ELISA;
Vietnam
- MeSH:
Adult;
Animals;
Antigens, Helminth/analysis/immunology;
*Disease Outbreaks;
Electron Transport Complex IV/genetics;
Enzyme-Linked Immunosorbent Assay;
Female;
Humans;
Larva;
Male;
Meat/*parasitology;
Mitochondria/genetics;
Muscles/parasitology/pathology;
Swine;
Trichinella spiralis/genetics/immunology/*isolation & purification;
Trichinellosis/*epidemiology/parasitology/pathology;
Vietnam/epidemiology
- From:The Korean Journal of Parasitology
2012;50(4):339-343
- CountryRepublic of Korea
- Language:English
-
Abstract:
The 5th outbreak of trichinosis occurred in a mountainous area of North Vietnam in 2012, involving 24 patients among 27 people who consumed raw pork together. Six of these patients visited several hospitals in Hanoi for treatment. Similar clinical symptoms appeared in these patients within 5-8 days after eating infected raw pork, which consisted of fever, muscle pain, difficult moving, edema, difficult swallowing, and difficult breathing. ELISA revealed all (6/6) positive reactions against Trichinella spiralis antigen and all cases showed positive biopsy results for Trichinella sp. larvae in the muscle. The larvae detected in the patients were identified as T. spiralis (Vietnamese strain) by the molecular analysis of the mitochondrial cytochrome c oxidase subunit III (cox3) gene.