Recent advances of molecular genetic characteristics of small cell lung cancer
10.3969/j.issn.1007-3969.2014.08.013
- VernacularTitle:小细胞肺癌分子遗传学研究进展
- Author:
Di LIU
;
Min FAN
- Publication Type:Journal Article
- Keywords:
Small cell lung cancer;
Genomic variation;
Gene expression profiling;
Oncogenic pathway
- From:
China Oncology
2014;(8):630-635
- CountryChina
- Language:Chinese
-
Abstract:
Small cell lung cancer (SCLC) is an aggressive malignancy with fairly poor prognosis. Innovative treatment based on improved understanding of the genetic alterations of SCLC is awaited. Recently, a number of potential targets or important oncogenic pathways have been identified by the next generation sequencing or other systematic genomic analysis in SCLC. In this review, we summarised the new ifndings of genetic characteristics in SCLC.
