Changes of serum homocysteine and lipoprotein-a in cerebral infarction patients and their correlation analysis
10.3969/j.issn.1673-4130.2014.16.016
- VernacularTitle:脑梗死患者血清同型半胱氨酸、脂蛋白a变化及其相关性分析
- Author:
Jing WANG
;
Shouyang XIA
;
Zhifeng LI
- Publication Type:Journal Article
- Keywords:
cerebral infarction;
cysteine;
apolipoproteins A
- From:
International Journal of Laboratory Medicine
2014;(16):2159-2160
- CountryChina
- Language:Chinese
-
Abstract:
Objective To observe the change of homocysteine(Hcy)and lipoprotein-a[Lp(a)]of cerebral infarction patients and perform the correlation analysis on them.Methods The serum Hcy and Lp(a)levels were detected in 230 patients with cerebral in-farction and 90 healthy controls.The detection results were performed the comparison between the groups and the correlation analy-sis.Results The serum Hcy and Lp(a)levels in the overall cerebral infarction group and the cerebral infarction group with in-creased Hcy were significantly higher than those in the healthy controls(P <0.01).The serum Hcy and Lp(a)levels in the cerebral infarction group without increased serum Hcy had no statistical difference compared with the healthy control group(P >0.05).The serum Hcy and Lp(a)levels in the overall cerebral infarction group had no statistical difference compared with the cerebral infarc-tion group with increased Hcy(P >0.05).The serum Hcy and Lp(a)levels in the overall cerebral infarction group and the cerebral infarction group with increased Hcy had statistical difference compared with the cerebral infarction group without increased Hcy (P <0.01).The serum Hcy in the overall cerebral infarction group is positively correlated with Lp(a)(r =0.859,P <0.01).Con-clusion The increase of serum Hcy and Lp(a)levels is closely related with the occurrence of cerebral infarction and has certain val-ue in the diagnosis of cerebral infarction,moreover serum Hcy is positively correlated with Lp(a).
