Evaluation of oxacillin disk test for screening Streptococcus pneumoniae by penicillin Etest method
10.3969/j.issn.1673-4130.2014.16.038
- VernacularTitle:青霉素 Etest 法评价肺炎链球菌苯唑西林的纸片筛选试验
- Author:
Xiangrong LUO
;
Chengyao LI
;
Jun YUAN
;
Honglin LI
;
Tingting JIN
;
Fangfang HU
- Publication Type:Journal Article
- Keywords:
streptococcus pneumoniae;
meningitis;
oxacillin
- From:
International Journal of Laboratory Medicine
2014;(16):2210-2211
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the oxacillin disk screening test for screening Streptococcus pneumoniae by the penicillin Etest method.Methods 96 clinically isolated non-meningitis strains of Streptococcus pneumoniae were collected.The sensitivity and spe-cificity of the oxacillin disc screening test was evaluated by the penicillin Etest method as a standard method for detecting the peni-cillin susceptibility.Results Among 96 non-meningitis strains of Streptococcus pneumoniae,the penicillin-susceptible Streptococcus pneumoniae(PSSP)strains detected by the penicillin Etest method accounted for 96.9%(93/96),the penicillin intermediate Strep-tococcus pneumoniae(PISP)strains accounted for 3.1%(3/96)and no penicillin resistant Streptococcus pneumoniae(PRSP)strain was found.But 16 PSSP strains were detected by the oxacillin disc screening test with the sensitivity of 17.2% and the specificity of 100.0%,respectively.The difference between the oxacillin disc screening test and the penicillin Etest method was statistically sig-nificant(χ2 =77,P <0.01 ).Conclusion The oxacillin disc screening test has the low sensitivity for preliminarily screening non-meningitis strains of Streptococcus pneumoniae.Most of Streptococcus pneumoniae must be detected by the minimum inhibitory concentration(MIC)methods such as the penicillin Etest method.
