Clinical Study on Tiaoxinyin in Treating Diabetic Cardiac Autonomic Neuropathy
10.3969/j.issn.1005-5304.2014.09.009
- VernacularTitle:调心饮治疗糖尿病心脏自主神经病变临床研究
- Author:
Xinye LIU
;
Yan WANG
;
Jinlong YANG
;
Xiao LI
- Publication Type:Journal Article
- Keywords:
Tiaoxinyin;
diabetic cardiac autonomic neuropathy;
heart rate variability
- From:
Chinese Journal of Information on Traditional Chinese Medicine
2014;(9):30-32
- CountryChina
- Language:Chinese
-
Abstract:
Objective To observe the clinical efficacy of Tiaoxinyin treatment for diabetic cardiac autonomic neuropathy (DCAN);To evaluate its efficacy and safety.Methods One hundred patients of DCAN were randomly divided into experimental group (51 cases) and control group (49 cases). Both groups were given basic treatment of diet control and Metformin hydrochloride tablets orally taking. Patients in the experimental group were given Tiaoxinyin, while patients in the control group were treated with Mecobalamin tablets for 8 weeks. Changes and untoward effects in blood glucose, blood fat and heart rate variability were observed before and after treatment so as to compare the efficacy of two groups.Results The total effective rate of the experimental group was 82.35% (42/51) and the control group was 63.27% (31/49), with statistical significance between the two groups (P<0.01). The TCM scores of the two groups decreased after treatment, with statistical significance compared with those before treatment (P<0.01). The difference in TCM scores between the two groups was significance (P<0.05). The level of FBG and 2 h PG in the two groups declined (P<0.05). Heart rate variability had statistical significance compared with that before treatment (P<0.05), with statistical significance between the two groups (P<0.05). No obvious adverse reaction was found.Conclusion Tiaoxinyin is effective and safe in treating DCAN and can improve the heart rate variability indicators in patients.
