Simultaneous Quantitative Analysis of Contents of Salidroside, Loganin and Polydatin in Buxin Ruanmai Granules by Multi-Components Assay with Single Marker
10.3969/j.issn.1005-5304.2014.09.027
- VernacularTitle:一测多评法测定补心软脉颗粒中红景天苷、马钱苷和虎杖苷含量
- Author:
Xun WANG
;
Ling FAN
;
Chao LU
;
Zhihui LIU
- Publication Type:Journal Article
- Keywords:
Buxin Ruanmai Granules;
QAMS;
relative correction factor;
Salidroside;
Loganin;
Polydatin
- From:
Chinese Journal of Information on Traditional Chinese Medicine
2014;(9):93-97
- CountryChina
- Language:Chinese
-
Abstract:
Objective To develop a method of quantitative analysis of multi-components with single marker (QAMS) for simultaneous determination of Salidroside, Loganin and Polydatin;To validate its accuracy and feasibility in Buxin Ruanmai Granules.Methods Salidroside was used as the internal reference substance, and the content of Salidroside in Buxin Ruanmai granules was determined by external standard method, with a purpose to establish its relative correction factor with Loganin and Polydatin. The contents of Loganin and Polydatin were calculated by the relative correction factor, and then multi-components assay with single marker was realized. The three contents in Buxin Ruanmai Granules were determined by both QAMS and external standard method, and their results were also compared.Results The results of 10 batches of samples by two methods did not show significant difference, which showed that relative correction factors had good reproducibility and credits.Conclusion The QAMS method can be used to quality evaluation with multiple indicators of Buxin Ruanmai Granules.
