Modeling methods and its mechanism of dilated cardiomyopathy
10.3969.j.issn.1671.7856.2014.008.011
- VernacularTitle:扩张型心肌病造模方法及机理
- Author:
Ying FENG
;
Jun WAN
- Publication Type:Journal Article
- Keywords:
Dilated cardiomyopathy;
Animal models;
Molding,method;
Mechanism
- From:
Chinese Journal of Comparative Medicine
2014;(8):47-52
- CountryChina
- Language:Chinese
-
Abstract:
The cause of dilated cardiomyopthy (DCM) has not been elucidated yet .The poor prognosis and lack of specific and effective treatment became a serious health problem .Therefore to establish animal models of DCM to study the pathogenesis and treatment is necessary and urgent .At present the molding method of DCM mainly includes drug induction, immunological induction and molecular biology , etc.This article reviews the mature and commonly used establishing methods and mechanism of DCM models .
