Clinical significance of anemia associated metabolin detection in patients with chronic renal failure
10.3969/j.issn.1673-4130.2014.16.023
- VernacularTitle:慢性肾功能不全患者贫血代谢物检测的临床意义
- Author:
Juan ZHANG
;
Shunjun LI
;
Wenfang HUANG
- Publication Type:Journal Article
- Keywords:
chronic renal fail;
total iron binding capacity;
vitamin B12
- From:
International Journal of Laboratory Medicine
2014;(16):2176-2178
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the clinical value of serum iron(Fe),total iron binding capacity(TIBC),serum ferritin(SF), folic acid(FA)and vitamin 12(ViB12 )in the diagnosis and treatment of chronic renal failure(CRF).Methods Fasting blood sam-ples were collected from 72 patients with CRF and 83 normal controls.Then the serum SF,ViB12 and FA contents were measured by the ARCHITECT i2000SR fully automatic chemiluminescence immunoassay analyzer;serum Fe and TIBC were detected by the VITORS FS 5.1 dry biochemical analyzer;RBC,HGB,HCT and MCV were analyzed by the Mindray BC-6800 complete automated blood counter.The detection results were performed the statistical analysis by the SPSS16.0 software.Results The levels of TIBC,RBC,HGB and HCT in the CRF patients were significantly lower than those in the control group(P <0.05);while the SF and ViB12 levels were significantly higher than those in the control group;serum Fe and MCV had no statistical difference compared with the control group(P >0.05);the FA level in the female patients was lower than that in the control group,but which in the male patients had no statistical differences compared with the control group(P >0.05).Conclusion The indexes of anemia associat-ed metabolin in the CRF patients can provide certain reference value for the diagnosis and treatment of chronic renal fail and has cer-tain guidance significance for correcting anemia caused by renal insufficiency.
