Analysis on Drug Using Regularity of Rehmanniae Radix in National Standard for Chinese Patent Drugs
10.3969/j.issn.1005-5304.2014.09.005
- VernacularTitle:《中华人民共和国卫生部药品标准·中药成方制剂》生地黄用药规律分析
- Author:
Qiang JIA
;
Dan SHEN
;
Defeng LI
;
Yi ZHANG
;
Hongjun YANG
- Publication Type:Journal Article
- Keywords:
Rehmanniae Radix;
National Standard for Chinese Patent Drugs;
composition principle of prescription;
data mining
- From:
Chinese Journal of Information on Traditional Chinese Medicine
2014;(9):17-20
- CountryChina
- Language:Chinese
-
Abstract:
Objective To analyze the composition principles of Chinese patent drugs containing Rehmanniae Radix;To provide reference for clinical application and new drug research and development.Methods Based on the software Traditional Chinese Medicine Inheritance Support System (V2.0), the authors built prescription database containing Rehmanniae Radix in National Standard for Chinese Patent Drugs (NSCPD). Then the authors adopted the statistical module by using data mining methods such as association rules and improved mutual information method, with a purpose to analyze the attending disease, combination rules and the core groups in prescriptions containing Rehmanniae Radix.Results In 357 prescriptions containing Rehmanniae Radix, 17 most commonly used drug combinations were mined. Meanwhile, two diseases, namely, insomnia and vertigo were chosen from the 22 diseases that Rehmanniae Radix was most frequently used to make deeper analysis, showing that Rehmanniae Radix can achieve different therapeutic effects through different compatibility.Conclusion Prescriptions containing Rehmanniae Radixin NSCPD mainly concentrate on clear heat and cool blood, and nourish Yin. The composition principles obtained from the research that Rehmanniae Radix used when curing different diseases can fully play the efficacy of RehmanniaeRadix and provide evidence for clinical scientific formulae.
