Research progress of rat models of type 2 diabetes induced by high calorie diet combined with streptozotocin
10.3969/j.issn.1005-4847.2014.04.020
- VernacularTitle:高脂饮食联合链脲佐菌素建立2型糖尿病大鼠模型的研究进展
- Author:
Junwei SHAO
;
Xun CAI
- Publication Type:Journal Article
- Keywords:
Type 2 diabetes mellitus;
Rat,model;
Streptozotocin;
High fat and calorie diet
- From:
Acta Laboratorium Animalis Scientia Sinica
2014;(4):90-93
- CountryChina
- Language:Chinese
-
Abstract:
The establishment of rat models of type 2 diabetes mellitus can provide an ideal animal experimental technology platform for the research of pathogenesis , prevention , diagnosis and treatment of diabetes mellitus and its com-plications .The establishment of type 2 diabetic rat models may be affected by various factors .In this paper , the main fac-tors, streptozotocin (STZ) application, high fat and calorie diet, selection and breeding of rats are reviewed , which will provide an important reference for the development of rat models type 2 diabetes.
