The relationship between the ultrasonic sign and expression of HMGB 1,VEGF in serum of hepatocellular carcinoma
10.3969/j.issn.1671-8348.2014.23.015
- VernacularTitle:肝细胞癌多普勒超声征象与血清 HMGB1、VEGF水平的关系
- Author:
Hong QI
- Publication Type:Journal Article
- Keywords:
hepatocellular carcinoma;
doppler ultrasound;
high mobility group box protein 1;
vascular endothelial growth factor
- From:
Chongqing Medicine
2014;(23):3017-3018
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the relationship between the ultrasonic sign and expression of HMGB1 ,VEGF in serum of hepatocellular carcinoma patients .Methods Doppler ultrasound was used to inspect the size of the tumor and to analyze the typing and flow classification .The ELISA was used to check the HMGB1 and VEGF in serum .Results The expression level of HMGB1 in nodular and massive group was higher than that in small modelgroup (53 .5 ± 4 .3) ng/mL .The expression level of HMGB1 in massive group(102 .9 ± 9 .7)ng/mL was higher than that in nodular group(76 .0 ± 6 .2) ng/mL(P<0 .05) .The VEGF among three groups had no difference(P>0 .05) .With the increase of flow classification ,the levels of HMGB1 and VEGF also increased(P<0 .05) .Conclusion The HMGB1 in serum has some connection with morphology types .The HMGB1 and VEGF in serum increase with the flow classification .
