Analysis of clinical manifestations and pathogenic septicemia of newborn babies late onsetsepsis in community acquired
10.3969/j.issn.1671-8348.2014.22.007
- VernacularTitle:不同胎龄新生儿社区获得性败血症晚发型临床表现及病原学分析
- Author:
Qili ZHOU
;
Lei REN
;
Jing BI
;
Jian GUO
;
Xia LIU
- Publication Type:Journal Article
- Keywords:
neonatal sepsis;
community acquired;
blood culture;
pathogenic bacteria;
drug susceptibility
- From:
Chongqing Medicine
2014;(22):2850-2852
- CountryChina
- Language:Chinese
-
Abstract:
Objective To summarize the clinical manifestation ,the main pathogenic bacteria distribution and drug resistance of neonatal community acquired sepsis late onset in our hospital .Methods Retrospectively analyse the clinical material of 122 cases (41 premature cases and 81 cases of full term) with neonatal community acquired sepsis late onset ,which were clinically diagnosed , from January 2009 to December 2012 in our hospital .Results The main clinical manifestation of neonatal community acquired sep-sis late onset was poor response(64 .7% ) ,repellent milk(57 .4% ) ,temperature changes(61 .5% ) ,and the respiratory tract and um-bilical region were the main infection ways .42 cases were checked out with pathogen in the 122 cases ,blood culture positive rate was 34 .4% ,and there was no statistically differences between the premature and the full term infant group ,In the 42 cases ,there were 29 cases with staphylococcus ,including 10 cases of staphylococcus aureus ,14 cases of coagulase negative staphylococcus and 5 cases of enterococcus ;and there were 10 cases are checked out with e .coli .All of the coccus detected were resistant to penicillin and erythromycin ,but sensitive to vancomycin ,teicoplanin ,linezolid .The e .coli was sensitive to amikacin ,imipenem ,meropenem ,and al-so had a higher sensitivity to cefazolin ,ceftriaxone ,cefepime ,cefoperazone and nitrofurantoin .Conclusion Blood culture positive rate is not high in neonatal community acquired sepsis late onset ,and its′clinical manifestations are nonspecific .The main pathogenic bacteria is coagulase negative staphylococcus ,staphylococcus aureus ,followed by escherichia coli .
