Efficay of skin roller pin combined with medication on cutaneous capillary hemangioma: an experimental study

VernacularTitle:皮肤滚针联合药物对鸡冠毛细血管作用的实验观察
Author: Qiang WEI ; Yu SUN ; Sida XU
Publication Type:Journal Article
Keywords: Hemangioma; Skin needle; Triamcinolone acetonide; Cockscomb
From: Chinese Journal of Medical Aesthetics and Cosmetology 2014;20(4):291-294
CountryChina
Language:Chinese
Abstract: Objective To investigate the role of the skin needle combined with different drugs in the treatment of capillary hemangioma,providing a theoretical basis for clinical treatment.Methods 50 Lai Henry chickens were randomly divided into five groups,each group of 10.Taking the comb as an animal model of capillary hemangioma of the skin,we used skin needle combined with different drugs onto the comb:Group A:bleomycin,B:triamcinolone acetonide,C:triamcinolone acetonide combined with bleomycin,D:saline group,and E.normal comb as a blank control group.We observed the changes of the comb and pathological changes,the number of capillaries under microscope in 1 d,7 d,14 d,21 d,and 28 d respectively.Results The color of the comb in each group gradually became lighter in different degrees,the number of capillaries reduced,the most significantly in group C,and most less change in group D.Conclusions Tumbling of the skin needle and drugs can effectively reduce the number of capillaries alone,and both effects can be cumulative.The best efficacy has been achieved with skin needle combined with bleomycin.