Establishment of a new experimental animal model of free superficial epigastric artery perforator flap in the rabbits
10.3760/cma.j.issn.1001-2036.2014.04.012
- VernacularTitle:兔腹壁浅动脉穿支皮瓣动物模型的建立
- Author:
Liming QING
;
Juyu TANG
;
Wei DU
;
Congyang WANG
;
Fang YU
;
Panfeng WU
- Publication Type:Journal Article
- Keywords:
Superficial epigastric artery;
Perforator flap;
Animal model;
Transplantation;
Microsurgery
- From:
Chinese Journal of Microsurgery
2014;37(4):364-367
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the feasibility of building a new model of free superficial epigastric artery perforator flap with New Zealand white rabbits.Methods Twenty-five healthy New Zealand white rabbits were used.Five rabbits were dissected to assess the vascular territory,the source and dimension of the superficial epigastric.According to the anatomic results,the superficial epigastric artery perforator flap were designed and harvested with 6 cm× 3 cm in the abdominal,anastomosis had been done between femoral artery/vein and carotid artery,jugular venous to build an animal model of transplantation of epigastric artery perforator flap.The donor sites were directly closured.Results Superficial epigastric artery originated from the proximal femoral artery,and the diameter of superficial epigastric artery was (0.15 ±0.02) mm,2-3 perforators support the areas of the skin of the lower abdominal wall.A rabbit died in the surgery because of anesthesia,the other animals were alive.The results showed that all flaps were survived in the experiment except a flap lost due to venous crisis.Conclusion The experimental model of free superficial epigastric artery perforator flap can be built in New Zealand white rabbits.It is a simple,practical and reliable model for future physiologic and pharmacologic studies.
