Prevalence and risk factor of atherosclerotic renal artery stenosis in patients with ischemic stroke
10.3760/cma.j.issn.1671-7368.2014.09.010
- VernacularTitle:缺血性卒中患者动脉粥样硬化性肾动脉狭窄的患病情况及危险因素分析
- Author:
Kai WANG
;
Guomin JIANG
;
Shaoqin LI
;
Feng TIAN
;
Zhongzhi JIA
;
Wenwei YUN
- Publication Type:Journal Article
- Keywords:
Atherosclerotic renal artery stenosis;
Ischemic stroke;
Prevalence;
Risk factor
- From:
Chinese Journal of General Practitioners
2014;13(9):745-749
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the prevalence and risk factors of atherosclerotic renal artery stenosis (ARAS) in patients with ischemic stroke (IS).Methods A total of 596 consecutive patients with ischemic stroke underwent cerebrovascular and renal angiography at our hospital from January 2008 to March 2013.Renal artery stenosis was defined as at least one of renal artery narrowing ≥ 50％ of luminal diameter.Multivariate logistic regression analysis was performed to investigate the association of the clinical variables with ARAS.Results Intracranial arterial stenosis (ICAS) was identified in 203 patients (34.1％),including 108 cases (18.5％) with arteriostenosis ≥ 50％.Extracranial arterial stenosis (ECAS) was identified in 250 patients (41.9％),including 149 cases (25.0％) with arteriostenosis ≥ 50％.The prevalence of ECAS was higher than that of ICAS(x2 =7.86,P ＜ 0.05).ARAS was identified in 77 patients (12.9％),and the prevalence of ARAS in patients with ECAS ≥50％ was higher than that in with ICAS ≥50％ (30.2 ％ vs.18.5％,x2 =4.52,P ＜0.05).Multivariate analysis showed that the age≥ 60 y (OR:2.48,P ＜ 0.05) and ECAS ≥ 50％ (OR:5.37,P ＜ 0.05) were independent risk factors for prevalence of ARAS.Conclusion ARAS is a relatively common finding among patients with ischemic stroke,suggesting that renal angiography should be performed in elderly IS patients,especially for those combined with severe ECAS.
