Impact of donor age on graft short-term outcome after right lobe adult living donor liver transplantation
10.3760/cma.j.issn.0254-1785.2014.07.008
- VernacularTitle:供者年龄对成人亲属活体右半供肝移植术后移植肝短期转归的影响
- Author:
Qian JI
;
Zhiqiang CHU
;
Wen SHEN
;
Hong ZHENG
;
Ji QI
- Publication Type:Journal Article
- Keywords:
Living donor;
Age;
Liver transplantation;
Liver regeneration
- From:
Chinese Journal of Organ Transplantation
2014;35(7):413-415
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the impact of donor age on graft short-term outcome after right lobe adult living donor liver transplantation (LDLT).Method Thirty living recipients were divided into 2 groups according to donor age:older donor group (O group,donor age ＞50,n =5) and younger donor group (Y group,donor age ＜30,n =25).Alanine transarninase (ALT),aspartate transaminase (AST),total bilirubin (TB),prothrombin time (PT) on the postoperative day 1 to 5 and graft liver regenerative ratio (LRR) on the postoperative month 0.5,1,3,and 6 between 2 groups were determined and compared.Result TB on postoperative day 1,2,3,4 and 5 was significantly higher in O group than in Y group there were significant differences between two groups (P＜0.01).There was no significant difference of other liver function parameters 2 groups (P ＞ 0.05).There was no significant difference in LRRs on the postoperative month 0.5,1,3 and 6 months postoperatively between 2 groups after LDLT (P＞0.05).Conclusion Although allografts from older donors in LDLT have prolonged jaundice than those of their younger counterparts,after strictly preoperative evaluation,donor age has little effect on short-term outcomes of graft after LDLT.
