Detection and genotyping of human papilloma virus in children with condyloma acuminatum in Weifang city, Shandong province
10.3760/cma.j.issn.0412-4030.2014.09.015
- VernacularTitle:山东省潍坊市尖锐湿疣患儿乳头瘤病毒检测和型别分析
- Author:
Manman BI
;
Xueliang ZHAO
- Publication Type:Journal Article
- Keywords:
Condylomata acuminata;
Child;
Human papillomavirus
- From:
Chinese Journal of Dermatology
2014;47(9):660-662
- CountryChina
- Language:Chinese
-
Abstract:
Objective To detect human papilloma virus (HPV) and to determine its genotype in children with condyloma acuminatum (CA) in Weifang city,Shandong province.Methods Swab specimens were collected from the surface of lesions of 24 children with CA.PCR/flow-through hybridization assay was performed to detect HPV and determine its genotypes in these specimens.Results Among the 24 specimens,95.8％ (23/24) were positive for HPV.Of the HPV-positive specimens,87.0％ (20/23) harbored single type of HPV,and 13.0％ (3/23) multiple types of HPV.The most common genotype was HPV6(9/23),followed by HPV16 (6/23),HPV11 (5/23),HPV58 (3/23),HPV18 (2/23),and HPV53 (1/23).Conclusions HPV 6,16,11,58 and 18 prevail in children patients with CA in Weifang city,Shandong province.Additionally,the HPV genotypes in children patients are similar to those in their close contacts.
