Quantitative analysis of contrast-enhanced ultrasound in acute rejection of kidney graft
10.3760/cma.j.issn.1004-4477.2014.07.016
- VernacularTitle:超声造影定量分析在移植肾急性排异中的应用研究
- Author:
Sheng ZHOU
;
Qing QI
;
Wanyuan HE
;
Zhengbiao JI
;
Yunjie JIN
;
Wenping WANG
- Publication Type:Journal Article
- Keywords:
Ultrasonography;
Microbubbles;
Kidney transplantation;
Graft rejection
- From:
Chinese Journal of Ultrasonography
2014;23(7):605-608
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the value of quantitative analysis of contrast-enhanced ultrasound in diagnosing acute rejection of kidney graft.Methods Sixty-seven patients with normal kidney grafts and thirty-five patients with acute rejection were recruited.In conventional ultrasound,the peak systolic velocity (PSV) and resistance index (RI) of segmental artery and interlobar artery were measured.In quantitative analysis of contrast-enhanced ultrasound,four regions of interest including renal cortex,medulla,segmental artery and interlobar artery were drew and three parameters including rising time(RT),time to peak(TTP) and mean transit time(mTT) were obtained.In addition,the difference in RT,TTP and mTT between the renal cortex and interlobar artery,as well as medulla and interlobar artery were calculated.Results The differences of PSV in interlobar artery between the two groups were statistically significant (P ＜0.05).The time-intensity curves of the whole kidney grafts,and the difference in RT and TTP between the renal cortex and interlobar artery were statistically different between two groups (P ＜0.05).Conclasions Quantitative analysis of contrast-enhanced ultrasound proved a quantitative method for diagnosing kidney allograft acute rejection.
