Case report of cervical intraspinal primitive neuroectodermal tumor and literature review

VernacularTitle:颈椎椎管内原始神经外胚层肿瘤一例并文献复习
Author: Zhong WANG ; Yong FENG ; Jianjun QI ; Ning SU ; Xiaojun ZHANG ; Zhong ZHANG
Publication Type:Journal Article
Keywords: Primitive neuroectodermal tumor; Cervical spine; Spine canal
From: Clinical Medicine of China 2014;30(8):813-816
CountryChina
Language:Chinese
Abstract: Objective To investigate the clinical characters and therapy of primitive neuroectodermal tumor(PNET).Methods A retrospective analysis was conducted.A 36-year-old female patient was showed pain and numbness of the right upper limb and back for 6 months.The cervical spine MRI showed a spindleshaped intradural mass right ventrolateral of spinal cord at C5-7 with in homogeneously enhancing.Surgery and pathologic examination confirmed that was PNET.Combiled with a series of literatures to analyse the clinical characters Results Surgery was performed to remove the tumor and decompression combined with radiotherapy.The pathologic examination and immunohistochemical analysis revealed that it was PNET.MRI identified local recurrence in spinal canal at 3 month later after surgery.Conclusion Spinal PNET is an uncommon intraspinal tumor with poor prognosis.Histopathology is the evidence of diagnosis.Optimal therapy has not yet been found.Surgical resection with the combination of chemo-radiotherapy or radiotherapy might get the better outcomes.Multidisciplinary treatment should be further clinical required.